Feb 012013

mamografia     Cuando un virus llamado “Herpes Simplex” (HSV) es genéticamente reprogramado  y es utilizado en ratas de laboratorio con células cancerosas humanas en su abdomen, se puede curar la difusión metastásica según un estudio reciente de científicos de la Universidad de Bolonia (Italia), este virus modificado tendría aplicación terapéutica en la lucha contra el cáncer de mama y cáncer de ovario.

Con esta alteráción genética el virus HSV ya no infecta las células ni causa las patologías que normalmente lo caracterizan, sino que actúa como un “arma” que ataca específicamente  las células tumorales que expresan el oncogén HER-2.

Este tipo de manipulación genética de virus se estudia hace años, no obstante una investigadora explica que, por lo general se debilita tanto el virus como medida de precaución, que sólo son efectivos en parte de los tumores. No obstante, la novedad de este estudio en particular, es que el virus “reprogramado” conserva su capacidad de matanza pero totalmente dirigida a las células tumorales,  siendo incapaz de infectar cualquier otra célula, lo que mantiene su valor terapéutico reduciendo los riesgos “colaterales” al paciente.

Tendremos que esperar más estudios para que estos descubrimientos se transformen en medidas terapéutcas utilizables en humanos, pero este nuevo virus modificado, el HSV oncolítico,  ofrece una expectativa digna de seguir con atención para el tratamiento de estas terribles enfermedades.


  18 Responses to “Un virus modificado genéticamente podría inhibir la metástasis en el cáncer de mama y ovario”

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